The ADE / CME provides an Open Circuit Detection feature that will pull up voltage in order to identify open channels. Make sure to tie both ends of any unused channels (+/-) to Channel 16- (ADE) or Channel 8- (CME), referred to as the Common Mode Reference Point (CMRP; isolated from system power/ground). Tying only one end of a channel, while leaving the opposing end open, may cause Open Circuit Detection to deliver unwanted voltages to your channels in use.